iPS Cell Technology
Product Pipeline
Published Research
iPS Cells
PLoS One
2011
Generation of Induced Pluripotent Stem Cells from CD34+ Cells across Blood Drawn from Multiple Donors with Non-Integrating Episomal Vectors
Blood
Human Lymphoblastoid B Cell Lines Reprogrammed to EBV-free Induced Pluripotent Stem Cells
Stem Cells
Optic Vesicle Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment (in press)
Proc Natl Acad Sci USA
Genetic Correction and Analysis of Induced Pluripotent Stem Cells from a Patient with Gyrate Atrophy
Nat Methods
Chemically Defined Conditions for Human iPS Cell Derivation and Culture
Efficient Generation of Transgene-free Induced Pluripotent Stem Cells from Normal and Neoplastic Bone Marrow and Cord Blood Mononuclear Cells
Clinical Pharmacology & Therapeutics
Opportunities for Use of Human iPS Cells in Predictive Toxicology
PLoS ONE
Efficient Feeder-Free Episomal Reprogramming with Small Molecules
2010
Derivation of Induced Pluripotent Stem Cells from Human Peripheral Blood T Lymphocytes
Essentials of Stem Cell Biology, 2nd Edition
2009
Induced Pluripotent Stem Cell Derivation
Science
Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
Nature
Induced Pluripotent Stem Cells from a Spinal Muscular Atrophy Patient
Genes Dev
2008
Pluripotent Stem Cell Lines
2007
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
2006
Human Embryonic Stem Cells Reprogram Myeloid Precursors Following Cell-Cell Fusion
Cardiomyocytes
Toxicology and Applied Pharmacology
Use of Human Stem Cell Derived Cardiomyocytes to Examine Sunitinib Mediated Cardiotoxicity and Electrophysiological Alterations
Am J Physiol Heart Circ Physiol
High Purity Human-induced Pluripotent Stem cell-derived cardiomyocytes: Electrophysiological Properties of Action Potentials and Ionic Currents
Stem Cells and Dev
Determination of the Human Cardiomyocyte mRNA and miRNA Differentiation Network by Finescale Profiling
Cellular Physiology and Biochemistry
The Electrophysiological Effects of Cardiac Glycosides in Human iPSC-derived Cardiomyocytes and in Guinea Pig Isolated Hearts
Toxicological Sciences
Estimating the Risk of Drug-Induced Proarrhythmia Using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes
BioPharm International
Industrialized Production of Human iPSC-derived Cardiomyocytes for Use in Drug Discovery and Toxicity Testing
J Cardiovasc Transl Res
Stem Cells and Their Derivatives: A Renaissance in Cardiovascular Translational Research
Biomaterials
The Microwell Control of Embryoid Body Size in Order to Regulate Cardiac Differentiation of Human Embryonic Stem Cells
Circ Res
Functional Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells
Expert Opinion on Drug Discovery
Human Embryonic Stem Cell-Derived Cardiomyocytes: Drug Discovery and Safety Pharmacology
Cardiac Regeneration and Stem Cell Therapy
Embryonic Stem Cells and Cardiogenesis
Human Cell Culture, Volume 6
Cardiomyocyte Derivation from Human Embryonic Stem Cells
Human Embryonic Stem Cell-derived Cardiomyocytes Can Be Maintained in Defined Medium without Serum
J Mol Cell Cardiol
Transplantation of Embryonic Stem Cells into the Infarcted Mouse Heart: Formation of Multiple Cell Types
Coron Artery Dis
2005
Embryonic Stem Cells: Differentiation into Cardiomyocytes and Potential for Heart Repair and Regeneration
Lancet
Blockade of HERG Channels by HIV Protease Inhibitors
2003
Human Embryonic Stem Cells Develop into Multiple Types of Cardiac Myocytes: Action Potential Characterization
Mol Pharmacol
2001
Cocaine Blocks HERG, but not KvLQT1+minK, Potassium Channels
Eur J Pharmacol
[3H]Dofetilide Binding to HERG Transfected Membranes: A Potential High Throughput Preclinical Screen
Cardiac Electrophysiology Review
2000
Proarrhythmia Related to Prolongation of Repolarization: Mechanisms, Monitoring, Prevention, and Management
J Cardiovasc Electrophys
1999
Block of Human Cardiac HERG K+ Channels by the Antihistamine Astemizole Metabolites Desmethylastemizole and Norastemizole
Mechanism of Block and Identification of the Verapamil Binding Domain to HERG Potassium Channels
Am J Physiol - Heart and Circ
1997
Blockage of the HERG Human Cardiac K+ Channel by the Gastrointestinal Prokinetic Agent Cisapride
Biophys J
1998
Properties of HERG Channels Stably Expressed in HEK 293 Cells Studied at Physiological Temperature
Hematopoietic Cells
Cell Cycle
Endothelial Origin of Mesenchymal Stem Cells
Stem Cells Dev
Generation of Red Blood Cells from Human Induced Pluripotent Stem Cells
Nat Protoc
Hematopoietic Differentiation and Production of Mature Myeloid Cells from Human Pluripotent Stem Cells
A Defined, Feeder-Free, Serum-Free System to Generate In Vitro Hematopoietic Progenitors and Differentiated Blood Cells from hESCs and hiPSCs
A Mesoderm-derived Precursor for Mesenchymal Stem and Endothelial Cells
Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells
Experimental Hematology
Molecular Profiling Reveals Similarities and Differences Between Primitive Subsets of Hematopoietic Cells Generated In Vitro from Human Embryonic Stem Cells and In Vivo During Embryogenesis
Methods Mol Biol
Directed Differentiation of Human Embryonic Stem Cells to Dendritic Cells
Curr Protoc Cell Biol (Ch 23: Unit 23.6)
Hematoendothelial Differentiation of Human Embryonic Stem Cells
J Immunol
Directed Differentiation of Human Embryonic Stem Cells into Functional Dendritic Cells through the Myeloid Pathway
Leukosialin (CD43) Defines Hematopoietic Progenitors in Human Embryonic Stem Cell Differentiation Cultures
Human Embryonic Stem Cell-derived CD34+ Cells: Efficient Production in the Coculture with OP9 Stromal Cells and Analysis of Lymphohematopoietic Potential
Hematopoietic Colony Forming Cells Derived from Human Embryonic Stem Cells
hES Cells
Secreted Proteoglycans Directly Mediate Human Embryonic Stem Cell-FGF2 Interactions Critical for Proliferation
Feeder-Independent Culture of Human Embryonic Stem Cells
Basic FGF Support of Human Embryonic Stem Cell Self-Renewal
Nat Biotechnol
Derivation of Human Embryonic Stem Cells in Defined Conditions
Basic FGF and Suppression of BMP Signaling Sustain Undifferentiated Proliferation of Human ES Cells
Human Embryonic Stem Cells
Clinical Applications for Human ES Cells (Chapter 14)
Homologous Recombination in Human Embryonic Stem Cells
2002
BMP4 Initiates Human Embryonic Stem Cell Differentiation to Trophoblast
Embryonic Stem Cell Lines Derived from Human Blastocysts
1995
Isolation of a Primate Embryonic Stem Cell Line
Neural Cells
Toxicol. Sci.
Novel Application of Human Neurons Derived from Induced Pluripotent Stem Cells for Highly Sensitive Botulinum Neurotoxin Detection
In Vitro Differentiation of Transplantable Neural Precursors from Human Embryonic Stem Cells