iCell Cardiomyocytes

iCell® Prototypes

Cellular Dynamics is committed to enabling the research community with access to relevant human biology through the rapid introduction of novel iPS cell-derived tissue cells.  To this end, CDI is engaged in the development of a variety of novel human iCell Prototypes.  The iCell Prototypes listed below are commercially available today.  Looking for another cell type?  Contact us for more information. 

iCell Astrocytes

iCell Astrocytes are a heterogeneous population of human astrocytes derived from iPS cells.  Astrocytes, the most abundant cell type within the CNS, are responsible for a wide variety of complex and essential functions in the CNS. In addition, the loss of or changes in normal astrocyte functions play a critical role in neurodegenerative diseases, including Alzheimer's  and Parkinson's diseases, as well as other neurological disorders. iCell Astrocytes provide a reliable source of high quality, high purity human astrocytes and are ideal for in vitro astrocyte-mediated neurotoxicity, targeted drug discovery, blood brain barrier modeling, and other life science research.

iCell Astrocytes express S100 calcium binding protein B (S100Β) and glial fibrillary acidic protein (GFAP) and secrete trophic factors with stimulation. These cells are shipped frozen as cryopreserved cells. Contact us for more information.

 
 

iCell Astrocytes
A highly pure astrocyte population demonstrating typical morphology (top) and expression of GFAP (bottom).

 
   

For More Information

We are actively seeking collaborative partnerships to develop this cell type and assays, and we welcome inquiries.

Email us or contact Cellular Dynamics:
+1 (608) 310-5100 | US toll-free (877) 310-6688

iCell Hematopoietic Progenitor Cells

Derived from human iPS cells, iCell Hematopoietic Progenitor Cells are human multipotent hematopoietic progenitor cells that can be further differentiated into diverse terminal cell types within the hematopoietic lineage.  The capacity to generate and provide highly purified human hematopoietic progenitor cells benefits multiple areas of biological research including basic hematopoiesis, cellular therapy, cancer immunotherapy, induced transplant tolerance, treatment for autoimmune diseases, and toxicity testing.

iCell Hematopoietic Cells are provided as a cyropreserved highly pure CD34+ population. Contact us for more information.



iCell Hematopoietic Progenitor Cells
iCell HPCs are multipotent precursor cells that give rise to a variety of hematopoietic cell types.

 

iCell HPC Multipotency
iCell HPC multipotency is demonstrated by their performance in colony-forming unit (CFU) assays. Note the presence of cellular processes in the CFU-MK assay indicating functional megakaryocytes.

 
   

For More Information

We are actively seeking collaborative partnerships to develop this cell type and assays, and we welcome inquiries.

Email us or contact Cellular Dynamics:
+1 (608) 310-5100 | US toll-free (877) 310-6688