iCell Cardiomyocytes

Predictive Multiparametric in vitro Assay Combinations for Cytotoxicity, Viability, Apoptosis, and ADME Applications with Hepatocytes and Human Stem Cell-derived Cardiomyocytes

Time & Location

CDIPromega

Tuesday, March 9
11:00am - noon
Salt Palace Convention Center
Room 155B


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Abstract

Combining bioluminescent and fluorescent cell-based assays allows multiparametric measurements from single samples, simplifying mechanistic studies. Multiplex approaches, using human-cell model systems, streamlines data collection, improves data quality, strengthens interpretation, and removes ambiguity. This seminar reviews multiplex applications of viability, cytotoxicity, apoptosis, cytochrome P450 induction/inhibition, and genetic reporter assays.

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