iCell Cardiomyocytes Literature

User Documentation

User's Guide: iCell Cardiomyocytes
(PDF)

Application Protocols

Dissociating Cardiomyocytes by Enzymatic Treatment
(PDF)

Extracting Total RNA
(PDF)

Immunofluorescent Labeling
(PDF)

New!

Measuring Cardiac Electrical Activity: Field Potential Detection with Axion Maestro Multielectrode Array
(PDF)

Measuring Cardiac Electrical Activity: Field Potential Detection with Multielectrode Array
(PDF)

Measuring Cardiac Activity: Impedance Detection with xCELLigence RTCA Cardio System
(PDF)

New!Measuring Cardiac Activity: Intracellular Calcium Flux Detection on the FLIPR Tetra System
(PDF)

Measuring Cardiac Electrical Activity: Manual Perforated Patch Clamp
(PDF)

Modeling Cardiac Hypertrophy: Endothelin-1 Induction with ELISA Analysis
(PDF)

Modeling Cardiac Hypertrophy: Endothelin-1 Induction with Flow Cytometry Analysis
(PDF)

Modeling Cardiac Hypertrophy: Endothelin-1 Induction with High Content Analysis
(PDF)

Modeling Cardiac Hypertrophy: Endothelin-1 Induction with qRT-PCR Analysis
(PDF)

Performing Bioenergetic Analysis: XF96 Extracellular Flux Analyzer
(PDF)

Using Transfection for siRNA Delivery
(PDF)

Safety Data Sheets (SDS)

iCell Cardiomyocytes
(PDF)

iCell Cardiomyocytes Plating Medium
(PDF)

iCell Cardiomyocytes Maintenance Medium
(PDF)

Datasheet

iCell Cardiomyocytes
(PDF)

Application Notes

Add-Mix-Read Assays for Assessing Cell Health Using an iPSC-derived Cardiomyocyte Cell Model
(HTML)

Applying Transfection Technologies to Create Novel Screening Models
(PDF)

Assaying Caspase Activity & Apoptosis
(PDF)

Assaying Cell Viability
(PDF)

Assaying Cytotoxicity
(PDF)

Assaying Mitochondrial Membrane Potential
(PDF)

Whitepaper

Use of Pluripotent Stem Cell-derived Cardiomyocytes to Understand Mechanisms of Cardiotoxic Compounds
(PDF, Promega Cell Notes, Issue 23)

Presentations

New!

Induced Pluripotent Stem Cell-derived Tissues and their Role in Developing Novel Assays for Drug Discovery
(PDF, presented at AIMBE 2013)

 

Human Induced Pluripotent Stem Cell Derived Cardiomyocytes Are a More Relevant Model Than H9C2 Cells for Assessing Mitochondrial Function in Drug Discovery and Toxicity Screens
(PDF, presented at SLAS2013)

  New!

What Makes a Cardiomyocyte a Cardiomyocyte?
(PDF, presented at HESI 2013)

 

Application of iPS Cell-derived Cells and a Novel Electrophysiology Platform for Neuronal and Cardiac Toxicity Evaluation and Drug Screening
(PDF, presented at SLAS2013)

 

Advanced Assays for In Vitro Toxicity Evaluation and Phenotypic Screening
(PDF, presented at SLAS2013)

 

Advancements in the Use of iPS Cell-derived Cells for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at SLAS2013)

Human iPS Cell Technology in Predictive and Mechanism-based Drug Discovery and Toxicity Testing Using Photometric-Based Assays
(PDF, presented at SOT Annual Meeting 2012)

 

Novel Assays for Drug Discovery and Toxicology Using Human iPS Cell-derived Neurons and Cardiomyocytes
(PDF, presented at SLAS2012)

 

Predictive Analysis of Cell Viability, Apoptosis and ADME/Tox Properties Using Multiparametric in vivo Assays and Human Induced Pluripotent Stem (iPS) Cell-derived Cardiomyocytes and Hepatocytes
(PDF, presented at SOT Annual Meeting 2011)

Stem Cell Toxicology and Drug Discovery: iCell Cardiomyocytes plus Molecular Devices Screening Platforms
(WebEx Recording)

Posters

Application of Human iPS Cell-derived Models for Highly Predictive Toxicity Screening
(PDF, presented at ELRIG 2013)

Development and Characterization of Human Induced Pluripotent Stem Cell-Derived Model Systems for Muscular Dystrophy Disease Modeling and Drug Development
(PDF, presented at the MDA 2013 Conference)

iCell® Cardiomyocytes: Human iPSC-derived Cardiomyocytes for Fully Functional and Comprehensive Assessments of NCE-mediated Effects.
(PDF, presented at HESI 2013)

Multiparameter In Vitro Assessment of Drug Effects on Cardiomyocyte Physiology Using iPS Cells
(PDF, presented at SOT Annual Meeting 2013)

Optical Measurements of Electrical Activity from hiPSC-derived Cardiomyocytes Is a Robust and High-throughput Method for Measuring NCE-effects on the Cardiac Action Potential
(PDF, presented at SOT Annual Meeting 2013)

Applications Development at CDI: Improving Workflows, Pushing Biology, and Enabling Screening
(PDF, presented at the CDI User Group Meeting 2012)

Human iPSC-derived Cells for Modelling Cellular Bioenergetics: Building a Metabolic Profile Using the XF Mito Stress Test
(PDF, presented at the CDI User Group Meeting 2012)

Advancements in the Use of iPS Cell-derived Systems for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at StemCONN 2013)

Implementation of Human iPSC-derived Cell Types Into High Throughput Screening Workflows
(PDF, presented at SLAS 2013)

iCell Neurons Literature

User Documentation

User's Guide: iCell Neurons
(PDF)

Application Protocols

Assessing Neurite Outgrowth: Quantification with High Content Screening
(PDF)

Immunofluorescent Labeling
(PDF)

New!

Measuring Neuronal Activity: Extracellular Single-unit Recordings on the Maestro Multielectrode Array
(PDF)

Plating into 1536-well Cell Culture Plates
(PDF)

Silencing Gene Expression: siRNA Delivery by Transfection
(PDF)

 

Performing Bioenergetic Analysis: XF96 Extracellular Flux Analyzer
(PDF)

Safety Data Sheets (SDS)

iCell Neurons
(PDF)

iCell Neurons Maintenance Medium
(PDF)

 

iCell Neurons Medium Supplement
(PDF)

Datasheet

iCell Neurons
(PDF)

Application Notes

Applying Transfection Technologies to Create Novel Screening Models
(PDF)

Presentations

Induced Pluripotent Stem Cell-derived Tissues and their Role in Developing Novel Assays for Drug Discovery
(PDF, presented at AIMBE 2013)

Application of iPS Cell-derived Cells and a Novel Electrophysiology Platform for Neuronal and Cardiac Toxicity Evaluation and Drug Screening
(PDF, presented at SLAS2013)

Advanced Assays for In Vitro Toxicity Evaluation and Phenotypic Screening
(PDF, presented at SLAS2013)

Advancements in the Use of iPS Cell-derived Cells for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at SLAS2013)

Characterizing Human iPS Cell-derived Neuronal Cultures: Expression and Function of Ion Channels and Receptors
(PDF, presented at SLAS2012)

Novel Assays for Drug Discovery and Toxicology Using Human iPS Cell-derived Neurons and Cardiomyocytes
(PDF, presented at SLAS2012)

Posters

High Content Screen for Compounds that Modulate Neurite Outgrowth and Retraction Using Human Induced Pluripotent Stem Cell-derived Neurons
(PDF, presented at ISSCR 2013)

Application of Human iPS Cell-derived Models for Highly Predictive Toxicity Screening
(PDF, presented at ELRIG 2013)

Development and Characterization of Human Induced Pluripotent Stem Cell-Derived Model Systems for Muscular Dystrophy Disease Modeling and Drug Development
(PDF, presented at the MDA 2013 Conference)

Applications of Human iPSC-derived Neurons Using High-content Image-based Assays
(PDF, presented at Society for Neuroscience Annual Meeting 2012)

Development and Characterization of Human iPSC-derived Neurons for Drug Discovery Applications
(PDF, presented at Society for Neuroscience Annual Meeting 2011)

High Content Neuronal Toxicity Assays Using iPS Cell-derived Neurons
(PDF, presented at SLAS2012)

Evaluation of Network Electrophysiology for Neurotoxicity Screening
(PDF, presented at Society for Neuroscience Annual Meeting 2012)

Optimization of Neuronal Cultures Derived from Human Induced Pluripotent Stem Cells for High Throughput Assays of Synaptic Function
(PDF, presented at ISSCR 2012)

Applications Development at CDI: Improving Workflows, Pushing Biology, and Enabling Screening
(PDF, presented at the CDI User Group Meeting 2012)

Human iPSC-derived Cells for Modelling Cellular Bioenergetics: Building a Metabolic Profile Using the XF Mito Stress Test
(PDF, presented at the CDI User Group Meeting 2012)

Advancements in the Use of iPS Cell-derived Systems for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at StemCONN 2013)

Implementation of Human iPSC-derived Cell Types Into High Throughput Screening Workflows
(PDF, presented at SLAS 2013)

iCell Astrocytes Literature

User Documentation

User's Guide: iCell Astrocytes Prototype
(PDF)

Datasheet

iCell Astrocytes
(PDF)

Safety Data Sheets (SDS)

iCell Astrocytes
(PDF)

iCell DopaNeurons Literature

User Documentation

User's Guide: iCell DopaNeurons
(PDF)

Application Protocol

New!Immunofluorescent Labeling
(PDF)

Safety Data Sheets (SDS)

iCell DopaNeurons
(PDF)

iCell DopaNeurons Maintenance Medium
(PDF)

iCell DopaNeurons Medium Supplement
(PDF)

iCell Nervous System Supplement
(PDF)

Presentation

Measuring Pharmaco Influences on Human iPSC-derived Neuronal Networks Using a Novel MEA Analysis Tool
(YouTube Video, Webinar, April 30, 2014)

Poster

Development of Human iPSC-derived Midbrain Dopaminergic Neurons for Disease Modeling
(PDF, presented at Parkinson’s Disease Keystone Symposia, 2014)

iCell Hepatocytes Literature

User Documentation

User's Guide: iCell Hepatocytes
Please contact Technical Support for this document

Application Protocol

Immunofluorescent Labeling
(PDF)

Safety Data Sheet

iCell Hepatocytes
HCC-100-010-001
(PDF)

Datasheet

iCell Hepatocytes
(PDF)

Application Note

Using iPSC-derived Hepatocytes as a Functional Model System for Human Hepatitis Research
(PDF)

Presentations

Induced Pluripotent Stem Cell-derived Tissues and their Role in Developing Novel Assays for Drug Discovery
(PDF, presented at AIMBE 2013)

Advanced Assays for In Vitro Toxicity Evaluation and Phenotypic Screening
(PDF, presented at SLAS2013)

Human iPS Cell Technology in Predictive and Mechanism-based Drug Discovery and Toxicity Testing Using Photometric-Based Assays
(PDF, presented at SOT Annual Meeting 2012)

Posters

Application of Human iPS Cell-derived Models for Highly Predictive Toxicity Screening
(PDF, presented at ELRIG 2013)

In Vitro Assessment of Drug Induced Liver Injury (DILI) Using a High Content Cellular Imaging System
(PDF, presented at SOT Annual Meeting 2013)

Characterization and Function of iPSC derived Hepatocytes for Use in Toxicity
(PDF, presented at SOT Annual Meeting 2013)

Comparison of Two Cell Model Systems, Primary Human Hepatocytes and hiPSC-derived Hepatocytes to Determine the Hepatoxicity of Three Candidate Drugs Developed for Rheumatoid Arthritis
(PDF, presented at SOT Annual Meeting 2012)

Predictive High-Content/High-Throughput Assays for Hepatotoxicity Using Induced Pluripotent Stem Cell (iPSC)-derived Hepatocytes
(PDF, presented at SOT 2012)

Applications Development at CDI: Improving Workflows, Pushing Biology, and Enabling Screening
(PDF, presented at the CDI User Group Meeting 2012)

Human iPSC-derived Cells for Modelling Cellular Bioenergetics: Building a Metabolic Profile Using the XF Mito Stress Test
(PDF, presented at the CDI User Group Meeting 2012)

Advancements in the Use of iPS Cell-derived Systems for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at StemCONN 2013)

Implementation of Human iPSC-derived Cell Types Into High Throughput Screening Workflows
(PDF, presented at SLAS 2013)

iCell Endothelial Cells Literature

User Documentation

User's Guide: iCell Endothelial Cells
(PDF)

Application Protocol

Assaying Barrier Function: xCELLigence RTCA Cardio System
(PDF)

Safety Data Sheets (SDS)

iCell Endothelial Cells
(PDF)

iCell Endothelial Cells Medium Supplement
(PDF)

Datasheet

iCell Endothelial Cells
(PDF)

Application Notes

Applying Transfection Technologies to Create Novel Screening Models
(PDF)

iCell Endothelial Cells - Assaying Cell Proliferation
(PDF)

iCell Endothelial Cells - Assaying Barrier Function
(PDF)

Posters

New!

Human Stem Cell-Derived Models of Endothelial Cell Morphogenesis: Label-Free Analysis of Invasion, Migration, and Sprouting Angiogenesis
(PDF)

Analysis of Endothelial Cell Morphogenesis Using iPSC-derived Endothelial Cells
(PDF, presented at the ELRIG Research & Innovation Showcase 2014)

Synthetic Extracellular Matrix for Investigating 3D Vascular Network Formation
(PDF, presented at the Society for Biomaterials 2013)

Application of Human iPS Cell-derived Models for Highly Predictive Toxicity Screening
(PDF, presented at ELRIG 2013)

Applications Development at CDI: Improving Workflows, Pushing Biology, and Enabling Screening
(PDF, presented at the CDI User Group Meeting 2012)

Human iPSC-derived Cells for Modelling Cellular Bioenergetics: Building a Metabolic Profile Using the XF Mito Stress Test
(PDF, presented at the CDI User Group Meeting 2012)

Advancements in the Use of iPS Cell-derived Systems for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at StemCONN 2013)

Implementation of Human iPSC-derived Cell Types Into High Throughput Screening Workflows
(PDF, presented at SLAS 2013)

MyCell Literature

Datasheet

MyCell Products
(PDF)

Application Protocol

New!

Collecting Blood and Isolating PBMCs
(PDF)

Safety Data Sheet

MyCell Products
(PDF)

iCell Hematopoietic Progenitor Cells Literature

Datasheet

iCell Hematopoietic Progenitor Cells
(PDF)

Safety Data Sheets (SDS)

iCell Hematopoietic Progenitor Cells
(PDF)

iCell Cardiac Progenitor Cells Literature

Datasheet

iCell Cardiac Progenitor Cells
(PDF)

Safety Data Sheets (SDS)

iCell Cardiac Progenitor Cells
(PDF)

iCell Skeletal Myoblasts Literature

User Documentation

User's Guide: iCell Skeletal Myoblasts
Please contact Technical Support for this document

Safety Data Sheets (SDS)

iCell Skeletal Myoblasts
(PDF)