Products and Services

Product Literature and Presentations

iCell Cardiomyocytes

User Documentation

User's Guide

iCell Cardiomyocytes
(PDF)

Application Protocols

Dissociating Cardiomyocytes by Enzymatic Treatment
(PDF)

Extracting Total RNA
(PDF)

Immunofluorescent Labeling
(PDF)

Measuring Cardiac Electrical Activity: Field Potential Detection with Axion Maestro Multielectrode Array
(PDF)

Measuring Cardiac Electrical Activity:
Field Potential Detection with Multielectrode Array
(PDF)

Measuring Cardiac Activity: Impedance Detection with xCELLigence RTCA Cardio System
(PDF)

Measuring Cardiac Electrical Activity:
Manual Perforated Patch Clamp
(PDF)

Modeling Cardiac Hypertrophy:
Endothelin-1 Induction with ELISA Analysis
(PDF)

Modeling Cardiac Hypertrophy:
Endothelin-1 Induction with Flow Cytometry Analysis
(PDF)

Modeling Cardiac Hypertrophy:
Endothelin-1 Induction with High Content Analysis
(PDF)

Modeling Cardiac Hypertrophy:
Endothelin-1 Induction with qRT-PCR Analysis
(PDF)

Performing Bioenergetic Analysis:
XF96 Extracellular Flux Analyzer
(PDF)

Using Transfection for siRNA Delivery
(PDF)

Material Safety Data Sheets (MSDS)

iCell Cardiomyocytes
(PDF)

iCell Cardiomyocytes Plating Medium
(PDF)

iCell Cardiomyocytes Maintenance Medium
(PDF)

Reference Materials

Datasheet

iCell Cardiomyocytes
(PDF)

Application Notes

Add-Mix-Read Assays for Assessing Cell Health Using an iPSC-derived Cardiomyocyte Cell Model
(HTML)

 

Applying Transfection Technologies to Create Novel Screening Models
(PDF)

 

Assaying Caspase Activity & Apoptosis
(PDF)

 

Assaying Cell Viability
(PDF)

 

Assaying Cytotoxicity
(PDF)

Assaying Mitochondrial Membrane Potential
(PDF)

Whitepapers

Use of Pluripotent Stem Cell-derived Cardiomyocytes to Understand Mechanisms of Cardiotoxic Compounds
(PDF, Promega Cell Notes, Issue 23)

Presentations

Induced Pluripotent Stem Cell-derived Tissues and their Role in Developing Novel Assays for Drug Discovery
(PDF, presented at AIMBE 2013)

 

Human Induced Pluripotent Stem Cell Derived Cardiomyocytes Are a More Relevant Model Than H9C2 Cells for Assessing Mitochondrial Function in Drug Discovery and Toxicity Screens
(PDF, presented at SLAS2013)

 

Quantification of Cardioactive Drug Effects Using xCELLigence RTCA Cardio and Human iPS-derived Cardiomyocytes
(Audio, presented at SOT Annual Meeting 2013)

 

What Makes a Cardiomyocyte a Cardiomyocyte?
(PDF, presented at HESI 2013)

 

Application of iPS Cell-derived Cells and a Novel Electrophysiology Platform for Neuronal and Cardiac Toxicity Evaluation and Drug Screening
(PDF, presented at SLAS2013)

 

Advanced Assays for In Vitro Toxicity Evaluation and Phenotypic Screening
(PDF, presented at SLAS2013)

 

Advancements in the Use of iPS Cell-derived Cells for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at SLAS2013)

 

Human iPS Cell Technology in Predictive and Mechanism-based Drug Discovery and Toxicity Testing Using Photometric-Based Assays
(PDF, presented at SOT Annual Meeting 2012)

 

Novel Assays for Drug Discovery and Toxicology Using Human iPS Cell-derived Neurons and Cardiomyocytes
(PDF, presented at SLAS2012)

 

Large-Scale Production of Human iPS Cell-derived Cardiomyocytes
(Flash Video, MP3, Audio Podcast, presented ACT Annual Meeting 2009)

 

Predictive Analysis of Cell Viability, Apoptosis and ADME/Tox Properties Using Multiparametric in vivo Assays and Human Induced Pluripotent Stem (iPS) Cell-derived Cardiomyocytes and Hepatocytes
(PDF, presented at SOT Annual Meeting 2011)

 

Predictive Multiparametric in vitro Assay Combinations for Cytotoxicity, Viability, Apoptosis, and ADME Applications with Hepatocytes and Human Stem Cell-derived Cardiomyocytes
(Flash Video, MP3, Audio Podcast, presented at SOT Annual Meeting 2010)

Stem Cell Toxicology and Drug Discovery: iCell Cardiomyocytes plus Molecular Devices Screening Platforms
(WebEx Recording)

Toxicology in the 21st Century: Stem Cells in Drug Discovery and Development
(Flash Video, MP3, Audio Podcast, presented at SOT Annual Meeting 2010)

Bibliography

Published Research
(HTML)

Posters

Application of Human iPS Cell-derived Models for Highly Predictive Toxicity Screening
(PDF, presented at ELRIG 2013)

 

Development and Characterization of Human Induced Pluripotent Stem Cell-Derived Model Systems for
Muscular Dystrophy Disease Modeling and Drug Development
(PDF, presented at the MDA 2013 Conference)

 

iCell® Cardiomyocytes: Human iPSC-derived Cardiomyocytes for Fully Functional and
Comprehensive Assessments of NCE-mediated Effects.
(PDF, presented at HESI 2013)

 

Multiparameter In Vitro Assessment of Drug Effects on Cardiomyocyte Physiology Using iPS Cells
(PDF, presented at SOT Annual Meeting 2013)

Optical Measurements of Electrical Activity from hiPSC-derived Cardiomyocytes Is a Robust and High-throughput Method for Measuring NCE-effects on the Cardiac Action Potential
(PDF, presented at SOT Annual Meeting 2013)

Applications Development at CDI: Improving Workflows, Pushing Biology, and Enabling Screening
(PDF, presented at the CDI User Group Meeting 2012)

Human iPSC-derived Cells for Modelling Cellular Bioenergetics: Building a Metabolic Profile Using the XF Mito Stress Test
(PDF, presented at the CDI User Group Meeting 2012)

Advancements in the Use of iPS Cell-derived Systems for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at StemCONN 2013)

Implementation of Human iPSC-derived Cell Types Into High Throughput Screening Workflows
(PDF, presented at SLAS 2013)

Technology Overview

Datasheet

Cellular Dynamics International: True Human Biology in a Dish
(PDF)

Poster

Reprogramming Human Peripheral Blood Cells
(PDF, presented at ISSCR 2009)

Bibliography

Published Research
(HTML)

iCell Endothelial Cells

User Documentation

 

User's Guide

iCell Endothelial Cells
(PDF)

Application Protocol

Assaying Barrier Function: xCELLigence RTCA Cardio System
(PDF)

Material Safety Data Sheets (MSDS)

iCell Endothelial Cells
(PDF)

iCell Endothelial Cells Medium Supplement
(PDF)

Reference Materials

Datasheet

iCell Endothelial Cells
(PDF)

Application Notes

Applying Transfection Technologies to Create Novel Screening Models
(PDF)

 

iCell Endothelial Cells - Assaying Cell Proliferation
(PDF)

iCell Endothelial Cells - Assaying Barrier Function
(PDF)

Poster

New!Analysis of Endothelial Cell Morphogenesis Using iPSC-derived Endothelial Cells
(PDF, presented at the ELRIG Research & Innovation Showcase 2014)

 

Synthetic Extracellular Matrix for Investigating 3D Vascular Network Formation
(PDF, presented at the Society for Biomaterials 2013)

 

Application of Human iPS Cell-derived Models for Highly Predictive Toxicity Screening
(PDF, presented at ELRIG 2013)

Applications Development at CDI: Improving Workflows, Pushing Biology, and Enabling Screening
(PDF, presented at the CDI User Group Meeting 2012)

Human iPSC-derived Cells for Modelling Cellular Bioenergetics: Building a Metabolic Profile Using the XF Mito Stress Test
(PDF, presented at the CDI User Group Meeting 2012)

Advancements in the Use of iPS Cell-derived Systems for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at StemCONN 2013)

Implementation of Human iPSC-derived Cell Types Into High Throughput Screening Workflows
(PDF, presented at SLAS 2013)

Technology Overview

Datasheet

Cellular Dynamics International: True Human Biology in a Dish
(PDF)

Poster

Reprogramming Human Peripheral Blood Cells
(PDF, presented at ISSCR 2009)

Bibliography

Published Research
(HTML)

iCell Hepatocytes

User Documentation

Safety Data
Sheet

iCell Hepatocytes – Pre-commercial
HCC-100-010-001-PC
HCC-100-010-005-PC
(PDF)

Reference Materials

Datasheet

iCell Hepatocytes
(PDF)

Application Notes

New!Using iPSC-derived Hepatocytes as a Functional Model System for Human Hepatitis Research
(PDF)

Presentations

Induced Pluripotent Stem Cell-derived Tissues and their Role in Developing Novel Assays for Drug Discovery
(PDF, presented at AIMBE 2013)

 

Advanced Assays for In Vitro Toxicity Evaluation and Phenotypic Screening
(PDF, presented at SLAS2013)

 

Human iPS Cell Technology in Predictive and Mechanism-based Drug Discovery and Toxicity Testing Using Photometric-Based Assays
(PDF, presented at SOT Annual Meeting 2012)

Posters

Application of Human iPS Cell-derived Models for Highly Predictive Toxicity Screening
(PDF, presented at ELRIG 2013)

 

In Vitro Assessment of Drug Induced Liver Injury (DILI) Using a High Content Cellular Imaging System
(PDF, presented at SOT Annual Meeting 2013)

 

Characterization and Function of iPSC derived Hepatocytes for Use in Toxicity
(PDF, presented at SOT Annual Meeting 2013)

 

Comparison of Two Cell Model Systems, Primary Human Hepatocytes and hiPSC-derived Hepatocytes to Determine the Hepatoxicity of Three Candidate Drugs Developed for Rheumatoid Arthritis
(PDF, presented at SOT Annual Meeting 2012)

Predictive High-Content/High-Throughput Assays for Hepatotoxicity Using Induced Pluripotent Stem Cell (iPSC)-derived Hepatocytes
(PDF, presented at SOT 2012)

Applications Development at CDI: Improving Workflows, Pushing Biology, and Enabling Screening
(PDF, presented at the CDI User Group Meeting 2012)

Human iPSC-derived Cells for Modelling Cellular Bioenergetics: Building a Metabolic Profile Using the XF Mito Stress Test
(PDF, presented at the CDI User Group Meeting 2012)

Advancements in the Use of iPS Cell-derived Systems for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at StemCONN 2013)

Implementation of Human iPSC-derived Cell Types Into High Throughput Screening Workflows
(PDF, presented at SLAS 2013)

Technology Overview

Datasheet

Cellular Dynamics International: True Human Biology in a Dish
(PDF)

Poster

Reprogramming Human Peripheral Blood Cells
(PDF, presented at ISSCR 2009)

Bibliography

Published Research
(HTML)

MyCell

User Documentation

Datasheet

MyCell Products
(PDF)

Material Safety Data Sheets (MSDS)

MyCell Products
(PDF)

 

Technology Overview

Datasheet

Cellular Dynamics International: True Human Biology in a Dish
(PDF)

Poster

Reprogramming Human Peripheral Blood Cells
(PDF, presented at ISSCR 2009)

Bibliography

Published Research
(HTML)

iCell Neurons

User Documentation

User's Guide

iCell Neurons
(PDF)

Application Protocols

Assessing Neurite Outgrowth:
Quantification with High Content Screening
(PDF)

Immunofluorescent Labeling
(PDF)

Plating into 1536-well Cell Culture Plates
(PDF)

New!Silencing Gene Expression:
siRNA Delivery by Transfection
(PDF)

Performing Bioenergetic Analysis:
XF96 Extracellular Flux Analyzer
(PDF)

Material Safety Data Sheets (MSDS)

iCell Neurons
(PDF)

iCell Neurons Maintenance Medium
(PDF)

iCell Neurons Medium Supplement
(PDF)

Reference Materials

Datasheet

iCell Neurons
(PDF)

Application Notes

Applying Transfection Technologies to Create Novel Screening Models
(PDF)

Presentations

Induced Pluripotent Stem Cell-derived Tissues and their Role in Developing Novel Assays for Drug Discovery
(PDF, presented at AIMBE 2013)

 

Application of iPS Cell-derived Cells and a Novel Electrophysiology Platform for Neuronal and Cardiac Toxicity Evaluation and Drug Screening
(PDF, presented at SLAS2013)

 

Advanced Assays for In Vitro Toxicity Evaluation and Phenotypic Screening
(PDF, presented at SLAS2013)

 

Advancements in the Use of iPS Cell-derived Cells for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at SLAS2013)

Characterizing Human iPS Cell-derived Neuronal Cultures: Expression and Function of Ion Channels and Receptors
(PDF, presented at SLAS2012)

Novel Assays for Drug Discovery and Toxicology Using Human iPS Cell-derived Neurons and Cardiomyocytes
(PDF, presented at SLAS2012)

Bibliography

Published Research
(HTML)

Posters

High Content Screen for Compounds that Modulate Neurite Outgrowth and Retraction Using Human Induced Pluripotent Stem Cell-derived Neurons
(PDF, presented at ISSCR 2013)

Application of Human iPS Cell-derived Models for Highly Predictive Toxicity Screening
(PDF, presented at ELRIG 2013)

 

Development and Characterization of Human Induced Pluripotent Stem Cell-Derived Model Systems for
Muscular Dystrophy Disease Modeling and Drug Development
(PDF, presented at the MDA 2013 Conference)

 

Applications of Human iPSC-derived Neurons Using High-content Image-based Assays
(PDF, presented at Society for Neuroscience Annual Meeting 2012)

 

Development and Characterization of Human iPSC-derived Neurons for Drug Discovery Applications
(PDF, presented at Society for Neuroscience Annual Meeting 2011)

High Content Neuronal Toxicity Assays Using iPS Cell-derived Neurons
(PDF, presented at SLAS2012)

Evaluation of Network Electrophysiology for Neurotoxicity Screening
(PDF, presented at Society for Neuroscience Annual Meeting 2012)

Optimization of Neuronal Cultures Derived from Human Induced Pluripotent Stem Cells for High Throughput Assays of Synaptic Function
(PDF, presented at ISSCR 2012)

Applications Development at CDI: Improving Workflows, Pushing Biology, and Enabling Screening
(PDF, presented at the CDI User Group Meeting 2012)

Human iPSC-derived Cells for Modelling Cellular Bioenergetics: Building a Metabolic Profile Using the XF Mito Stress Test
(PDF, presented at the CDI User Group Meeting 2012)

Advancements in the Use of iPS Cell-derived Systems for In Vitro Disease Modeling and Phenotypic Screening
(PDF, presented at StemCONN 2013)

Implementation of Human iPSC-derived Cell Types Into High Throughput Screening Workflows
(PDF, presented at SLAS 2013)

Technology Overview

Datasheet

Cellular Dynamics International: True Human Biology in a Dish
(PDF)

Poster

Reprogramming Human Peripheral Blood Cells
(PDF, presented at ISSCR 2009)

Bibliography

Published Research
(HTML)

iCell Astrocytes

Datasheet

iCell Astrocytes
(PDF)

iCell Hematopoietic Progenitor Cells

Datasheet

iCell Hematopoietic Progenitor Cells
(PDF)

iCell Cardiac Progenitor Cells

Datasheet

iCell Cardiac Progenitor Cells
(PDF)